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NAD+ IV Therapy in Sioux Falls, South Dakota

Cellular energy, DNA repair, and longevity

Medically reviewed by Jonathan Belmore, MD|Updated 2026-06-01
$250 – $505 per session~90 minutesSioux Falls, SD
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NAD+ IV Therapy in Sioux Falls

IVList lists 4 providers offering NAD+ IV therapy in Sioux Falls, South Dakota — including Encompass Wellness & Aesthetics, Vital Flow Infusions, LIVE Hydration Spa Sioux Falls. All are in-clinic locations, with an average rating of 5★ across local reviews. Compare pricing and book NAD+ below.

Sioux Falls residents have access to 4 IV therapy providers across the Minnehaha County area. IV therapy sessions in Sioux Falls typically range from $99 to $500 depending on the treatment. Whether you need a quick hydration drip, immune boost, or NAD+ longevity infusion, Sioux Falls's IV therapy clinics have you covered. Serving a community of 207,648 residents.

What is NAD+ IV Therapy?

NAD+ (nicotinamide adenine dinucleotide) is a coenzyme present in every cell, essential for energy metabolism, DNA repair, and the activation of longevity proteins called sirtuins. NAD+ levels decline 50%+ by middle age. IV NAD+ therapy delivers this critical molecule directly to cells at concentrations impossible to achieve orally, supporting cellular regeneration, cognitive function, and anti-aging pathways.

Key Benefits

  • Enhanced cellular energy
  • DNA repair activation
  • Sirtuin (longevity protein) activation
  • Improved cognitive clarity
  • Mood and mental health support
  • Athletic performance
  • Addiction recovery support

Best For

  • Anti-aging and longevity
  • Cognitive performance
  • Chronic fatigue syndrome
  • Athletic recovery
  • Addiction recovery support
  • Neurological health
  • Biohackers and longevity enthusiasts

NAD+ Pricing in Sioux Falls

Local pricing estimates based on market data for Sioux Falls, South Dakota.

Starting From

$250

Typical High

$505

Session Length

90 min

Prices vary by provider, add-ons, and mobile vs. clinic delivery. Mobile services may add a $25–$50 travel fee.

What's in a NAD+ IV Drip?

NAD+ (Nicotinamide Adenine Dinucleotide)Normal SalineOptional: B-ComplexOptional: Amino Acids

NAD+ IV Providers in Sioux Falls

4 listed

Encompass Wellness & Aesthetics

Medical Clinic
5.0(303 reviews)
4301 W 57th St #160, Sioux Falls, SD 57108
(605) 740-0414
encompass-wellness.com/?utm_source=google&utm_medium=organic&utm_campaign=gbp_siouxfalls

Drips Available

hydrationmyers-cocktailhangoverimmunityvitamin-c+5 more
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Vital Flow Infusions

IV Bar
5.0(251 reviews)
119 S Main Ave, Sioux Falls, SD 57104
(605) 223-1503
vitalflowinfusions.com/?utm_source=google&utm_medium=organic&utm_term=gbp-listing

Drips Available

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LIVE Hydration Spa Sioux Falls

IV Bar
5.0(24 reviews)
5011 S Louise Ave, Sioux Falls, SD 57108
(531) 999-3030
livehydrationspa.com/live-hydration-spa-sioux-falls/

Drips Available

hydrationmyers-cocktailhangoverimmunityvitamin-c+3 more
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Prime IV Hydration & Wellness - Sioux Falls

IV Bar
4.9(56 reviews)
7208 S Lyncrest Pl, Sioux Falls, SD 57108
(605) 231-9263
primeivhydration.com/locations/south-dakota/sioux-falls-57108/

Drips Available

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FAQ — NAD+ IV Therapy in Sioux Falls

NAD+ IV therapy in Sioux Falls, South Dakota typically costs $250–$505 per session. That range reflects the 4 Sioux Falls providers offering NAD+ in our directory. Mobile visits usually add a $25–$50 travel fee, and add-ons or multi-session packages can change the total.
IVList lists 4 Sioux Falls providers offering NAD+, including Encompass Wellness & Aesthetics. Most operate as in-clinic locations in and around Sioux Falls. Listed Sioux Falls providers average 5★ in reviews. Compare them on this page and request a quote to get matched.
A NAD+ IV session in Sioux Falls typically takes about 90 minutes, plus 10–15 minutes for intake at your first visit.
NAD+ is most often used for Anti-aging and longevity, Cognitive performance, Chronic fatigue syndrome, Athletic recovery. NAD+ (nicotinamide adenine dinucleotide) is a coenzyme present in every cell, essential for energy metabolism, DNA repair, and the activation of longevity proteins called sirtuins.
NAD+ IV therapy is generally safe when administered by a licensed RN or NP at a reputable Sioux Falls provider operating under a medical director. It may not be appropriate for people with Active cancer (consult oncologist), Pregnancy, Severe liver disease — always complete a health intake first.
Our current Sioux Falls listings for NAD+ are in-clinic, but mobile IV service is expanding across South Dakota. Ask local providers about home or hotel delivery, which usually adds a $25–$50 travel fee.

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