How Often Should You Get IV Therapy? — Frequency Guide by Goal

The right IV therapy frequency depends on your goal, drip type, and health status. Here is a complete breakdown.

There is no single correct answer to how often you should get IV therapy — it depends entirely on your health goal, which drip you are receiving, your baseline health, and whether you are doing an initial loading protocol or ongoing maintenance. A hangover recovery drip is an as-needed, event-based treatment. NAD+ anti-aging therapy is a structured multi-session protocol. General wellness maintenance sits somewhere in between. This guide gives you the recommended frequency for every major use case.

Recommended IV Therapy Frequency by Goal

GoalRecommended Frequency
Hangover recoveryAs needed (per event)
General wellnessMonthly
Immune supportMonthly or seasonal
Athletic performanceWeekly during training blocks
Energy & fatigueBiweekly to start, monthly maintenance
Anti-aging (NAD+)4-session protocol, then monthly
Beauty / GlutathioneWeekly × 4–6 sessions, then monthly
POTS managementWeekly to monthly (doctor-directed)

How Long Do IV Therapy Benefits Last?

Understanding how long each drip type lasts in your body helps you time sessions appropriately:

Hydration / Hangover

24–48 hours

Fluid and electrolyte effects are relatively short-lived — ideal for event-based use.

B Vitamins / Myers'

3–7 days

Water-soluble B vitamins elevate blood levels for several days before naturally declining.

Glutathione / Beauty

1–2 weeks (cumulative)

Skin and antioxidant benefits build with repeated sessions — consistency is essential.

NAD+

2–4 weeks per session

NAD+ has the longest-lasting per-session effects, supporting cellular energy and repair.

Vitamin C / Immunity

1–2 weeks

High-dose IV vitamin C elevates plasma levels significantly above oral supplementation for 1–2 weeks.

Building Your IV Therapy Protocol

An IV therapy "protocol" refers to a structured series of sessions designed to achieve a specific health outcome — as opposed to a one-off appointment. For goals like NAD+ anti-aging, glutathione beauty, or chronic fatigue recovery, a single session is unlikely to produce the desired result. Clinics typically recommend a loading phase followed by maintenance.

A typical starter protocol looks like this: four sessions over four weeks (weekly), designed to establish elevated nutrient levels in the body. After the loading phase, most patients transition to monthly maintenance sessions to sustain those elevated levels. This approach is used for Myers\' Cocktail wellness programs, NAD+ anti-aging protocols, and glutathione skin treatments.

From a financial perspective, most clinics offer monthly membership packages that reduce per-session costs by 30–50% compared to single-session pricing. For anyone planning to receive IV therapy more than once per month, a membership almost always makes financial sense.

Can You Get IV Therapy Too Often?

For the most common IV drip components — saline, B vitamins, vitamin C, and electrolytes — these are water-soluble and excess amounts are excreted by your kidneys. Weekly sessions of standard wellness drips are generally considered safe for healthy adults.

  • NAD+ therapy is typically limited to monthly after a loading protocol — more frequent sessions do not proportionally increase benefit.
  • Fat-soluble vitamin add-ons (vitamins A, D, E, K) can accumulate — use these sparingly and follow provider guidance.
  • People with kidney disease or heart conditions should consult their physician before establishing any IV therapy schedule — excess fluid or certain minerals can be problematic.
  • A spacing of at least 1–2 weeks between sessions is the general minimum for most drip types to allow your body to process and use the nutrients delivered.

How Often Should You Get IV Therapy — Frequently Asked Questions

For most drips containing B vitamins, vitamin C, and electrolytes, weekly sessions are generally considered safe. NAD+ therapy is typically done monthly after an initial protocol, as the effects last 2–4 weeks. Fat-soluble vitamins and certain add-ons have upper limits — always follow your provider's guidance on spacing.
It depends on the nutrients delivered. Hydration and hangover effects last 24–48 hours. B vitamins from a Myers' Cocktail provide elevated levels for 3–7 days. Glutathione and beauty benefits are cumulative, building over weeks. NAD+ effects can last 2–4 weeks per session. Vitamin C immunity support lasts approximately 1–2 weeks.
Weekly IV therapy makes sense for specific goals — athletes in intense training blocks, patients on a NAD+ loading protocol, or those doing a glutathione series for skin. For general wellness maintenance, monthly is the most common cadence. Your provider can help you determine the right frequency for your specific situation.
Most clinics recommend a 4-session starter series — one session per week for four weeks — to establish a meaningful nutrient baseline. After this, many patients transition to monthly maintenance sessions. This approach is common for wellness, energy, anti-aging, and beauty goals.
Yes — regular IV therapy sessions help maintain higher baseline levels of key nutrients compared to sporadic one-off sessions. This is particularly true for glutathione (beauty and anti-aging), NAD+ (cellular energy and longevity), and vitamin C (immunity). Consistency produces better long-term outcomes than occasional sessions.